Ozempic and Mounjaro are FDA approved medications for Type 2 diabetes treatment that are helping lose weight due to their weight management capability. FDA approval date for Ozempic was December 5, 2017, and for Mounjaro May 13, 2022.
In this article we will explore their differences in various contexts relevant to patients.
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Why is Semaglutide getting so popular right now?
Because it works. 92% members have achieved lasting weight loss.
Ozempic and Mounjaro are regulating blood glucose levels by increasing insulin sensitivity while inhibiting glucagon release. They are curbing cravings and inducing satiety which make people eat less and subsequently lose weight.
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Peter
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Mounjaro and Ozempic are beneficial for heart health:
Mounjaro is highly effective in glycemic control in individuals with Type 2 diabetes and superior to Ozempic.
Ozempic is the brand name for the drug Semaglutide, which is a GLP-1 receptor agonist. GLP-1 is delaying gastric emptying while boosting insulin release and inhibiting glucagon release.
Mounjaro’s active ingredient is Tirzepatide, a dual GLP-1/GIP receptor agonist. GIP enhances GLP-1 effects on insulin and glucagon and aids fat burning while affecting areas of the brain that control appetite and satiety.
Ozempic comes in multidose pens with disposable Novofine needles, whereas Mounjaro comes in single-dose disposable pens. Mounjaro is available in six doses (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg and 15 mg) and Ozempic is available in 4 doses (0..25 mg, 0.5 mg, 1 mg and 2 mg).
The price for Ozempic is $935.77, while Mounjaro is $1,069.08 for a month’s supply without insurance coverage. Ozempic and Mounjaro are covered by most insurance plans if prescribed as diabetes medicine, while off-label prescription for weight loss most likely won’t be covered. Ozempic Savings Card and Mounjaro Savings Card can help reduce the cost to $25 per month for private insurance users. Uninsured patients could be eligible for Ozempic and Mounjaro at no cost through Novo Nordisk Patient Assistance Program and Lilly Cares® Foundation Patient Assistance Program.
Ozempic and Mounjaro have similar the most common side effect profile which mostly improves over time and includes: nausea, abdominal pain, burping, constipation, diarrhea, dyspepsia and vomiting. Serious side effects that require immediate medical attention are:
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If a patient is not content with the current medication (Ozempic or Mounjaro) the doctor can suggest switching to another one. The new medication can be taken at a low dosage the week after stopping the first one.
Studies suggest that Mounjaro may be more effective in managing blood sugar levels and weight loss than Ozempic.
Patient suitability for either Ozemic or Mounjaro should be assessed by a doctor who will take into consideration the patient’s medical history, ongoing health conditions, current medications, treatment goals and drug’s market availability.
No, it is not recommended to take Ozempic and Mounjaro at the same time.
Drinking alcohol while taking Ozempic or Mounjaro can exacerbate side effects, slow down weight loss and cause drop in blood glucose levels, so manufacturers recommend abstaining from alcohol entirely.
It takes 16 weeks with 5 mg and 12 weeks with 10 mg and 15 mg of Mounjaro to lose ≥5% of body weight.
Ozempic and Mounjaro are regulating blood glucose levels with a high efficacy rate, but clinical trial outcomes demonstrated that Mounjaro is superior to Ozempic in glycemic control and concomitant weight loss.
Ozempic and Mounjaro have the same administration method and treatment duration, whereas they differ in dosage forms.
There are 397 drug interactions with Tirzepatide and 251 drug interactions with Semaglutide so it is crucial to consult the health care provider prior to beginning the treatment with either of these two medications to avoid harmful combination effects.
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