Horny Goat Weed vs. Viagra: Which is Better for Erectile Dysfunction?

The main difference is that Horny Goat Weed is a natural alternative to prescription drugs like Viagra, appealing to those who prefer natural therapies over medications.

Jack & Jill

Medically Reviewed By Mostafa Elhennawy MS, Pharm D

February 14, 2025

When it comes to treating erectile dysfunction (ED), men often find themselves choosing between natural remedies such as Horny Goat Weed and modern medications like Viagra.

Horny Goat Weed is a centuries-old herbal remedy rooted in traditional Chinese medicine, while Viagra is an FDA-approved medication known for its effectiveness. Each treatment has unique benefits, mechanisms of action, and side effect profiles.

This article will compare these two therapies’ effectiveness, safety, and suitability for different lifestyles and health needs to help you decide which will best suit your personal preferences and health goals.

About the Experts

We champion clinical excellence through evidence-based, personalized care. We are also commited to affordable clinically-led care for everyone. With features like same day doctor appointments, judgement free care, 24/7 medical chat support, 50+ pharmacy providers, free shipping we are on to something.

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What is Horny Goat Weed (Icariin)?

Horny Goat Weed is also known as Epimedium, Yin Yang Huo, and “herbal Viagra.” Its active component, icariin, improves blood circulation to the genitals and relaxes smooth muscle tissue. Apart from treating ED, Horny Goat Weed provides diverse therapeutic benefits, including slowing aging, preventing osteoporosis, boosting immunity, alleviating depression, protecting against myocardial ischemia, and combating cancer. Traditional Chinese medicine links aging to kidney qi weakness, often manifesting as sexual dysfunction, contrasting with modern medical views that separate aging and sexual health.

Two clinical trials examined the effects of Horny Goat Weed on aged males. A 2013 study in Thailand evaluated 61 patients with mild to moderate ED using herbal medicine containing Epimedium versus placebo. The Epimedium group showed greater improvement in ED compared to placebo. In Japan, a trial studied Epimedium 49 aging males with mild to severe symptoms. Over six months, Epimedium recipients showed improvements in somatic and psychological aging outcomes, including ED.

Customer Reviews

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“I have been getting/taking ED meds through a regular drug store for a few years before my girlfriend saw an ad for. We decided to try it and it has been great!”

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“Sildenafil at a fraction of the price I would pay at a pharmacy!”

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John K.

“I couldn’t be happier. The ED treatment has done wonders.”

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How Does Viagra Work?

The demand for ED treatment has grown, and Viagra, the first PDE5 (phosphodiesterase type 5) inhibitor, has changed how the condition is treated medically. It revolutionized ED treatment, with over 30 million men treated globally. Nitric Oxide (NO) is released in the penis during sexual arousal, leading to Cyclic guanosine Monophosphate (cGMP) accumulation. Cyclic GMP improves penile blood flow by helping the muscles in the penis relax. ED is associated with decreased cGMP levels because PDE5 degrades cGMP in the penis, making erections difficult to achieve. Sildenafil, Viagra’s active substance, enhances the effect of NO by inhibiting PDE5, which helps sustain an erection. Viagra also treats idiopathic pulmonary hypertension and may improve endothelial function.

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Horny Goat Weed vs. Viagra: What is the Difference?

The main difference is that Horny Goat Weed is a natural alternative to prescription drugs like Viagra, appealing to those who prefer natural therapies over medications. Viagra, approved by the FDA, is a well-researched and widely accepted treatment for erectile dysfunction, available by prescription.

Benefits for ED

Icariin, the active ingredient in Horny Goat Weed, has been suggested to increase NO synthesis in the penis, inhibit PDE5, positively affect nitrergic nerves, enhance smooth muscle proliferation, and mimic endogenous androgens. Like with other herbal supplements, there’s limited evidence of Horny Goat Weed’s health benefits. Viagra treats ED by improving blood flow to the penis during sexual arousal. Viagra benefits about 70% of men, with better responses in mild ED cases than severe ones. Higher doses produce stronger effects but also more side effects.

Side Effects

Horny Goat Weed may cause:

a rapid, irregular heartbeat
sweating or feeling hot
an increase in energy
mood changes
fainting
low blood pressure
an increased risk of bleeding
prolonged blood clotting
severe breathing problems
spasms
dizziness
vomiting
dry mouth
thirst
nose bleed

Patients with hormone-sensitive cancers or heart disease should avoid Horny Goat Weed.

Viagra’s side effect profile includes:

headache
nausea
hot flushes
indigestion
stuffy nose
dizziness
temporary vision issues
chest pain
myalgia
nosebleed
dry eyes
fainting
tinnitus
low blood pressure
sudden hearing loss

Viagra may interact with prescriptions, such as blood pressure medications and antidepressants.

How to Use

Horny Goat Weed is available as a capsule, tablet, powder, or tea. Horny Goat Weed can also be found in combination with other supplements. There is insufficient reliable information regarding an appropriate dose of Horny Goat Weed. Before using, follow the directions on the product label and consult with a healthcare professional. Viagra is taken orally in 25 mg, 50 mg, and 100 mg doses. It is taken 1 hour before intercourse, with a maximum frequency of once daily. Sexual stimulation is required for effectiveness. Onset occurs within 14 minutes for 35% of patients. A high-fat meal delays absorption, but alcohol does not impact regular doses.

Pricing

In general, Horny Goat Weed is less expensive than Viagra, but the prices of both can vary greatly. Horny Goat Weed prices vary depending on the brand, added ingredients, and dose. For instance, a 750 mg oral tablet is around $12.52 for a supply of 90 tablets. The cost for Viagra 50 mg oral tablet is around $2,771 for a supply of 30 tablets. The cost for sildenafil 100 mg oral tablet is around $10 for a supply of 2 tablets.

Is Horny Goat Weed Like Viagra?

Horny Goat Weed acts similarly to Viagra, primarily by blocking PDE5. It offers a natural alternative to Viagra. While some studies suggest that it may help boost libido and erectile function, more research is needed to confirm these findings.

Does Horny Goat Weed work as fast as Viagra?

Horny Goat Weed should be taken orally 90 minutes before planned sexual activity. Horny Goat Weed may stay in the system for 12 to 36 hours. Viagra expires after about 24 hours. Another PDE5 inhibitor, tadalafil, may expire after 72 hours. Viagra is usually taken only when needed, 30 minutes to 1 hour before sexual activity. It can be taken up to 4 hours before sexual activity.

Which Is Better for Erectile Dysfunction?

Horny Goat Weed boosts sexual stamina but is not as effective as Viagra in treating erectile dysfunction. Viagra is FDA-approved and proven effective, while Horny Goat Weed lacks conclusive scientific support for treating ED. Consult a healthcare provider to determine the best option. For supplements, ensure quality by buying from reliable sources to avoid contamination or mislabeling.

Frequently Asked Questions

Can you use Horny Goat Weed and Viagra together?

No, using Horny Goat Weed extract and Viagra together should be avoided due to possible herb-drug interactions.

How long does the effect of Horny Goat Weed last compared to Viagra?

Horny Goat Weed may stay in the system for 12 to 36 hours, though this is not FDA-confirmed. Viagra remains effective for 30 minutes to 4–5 hours, with some cases extending up to 12 hours.

Is Icariin suitable for long-term use for ED?

Yes, adults have safely used Horny Goat Weed extract with phytoestrogens for up to two years and Icariin-containing extracts for up to six months. Prolonged or high-dose use may be unsafe and cause severe side effects, such as breathing difficulties.

Key Takeaways

Horny Goat Weed is a traditional Chinese medicine believed to improve sexual performance, whereas Viagra is a clinically proven prescription medication for the treatment of ED.

Horny Goat Weed is not as effective as Viagra in treating ED, but it is an excellent choice for those looking for natural alternatives.

Viagra is more expensive and requires a prescription to purchase, whereas Horny Goat Weed can be purchased over the counter for a lower price.

Sources

Shindel AW, Xin ZC, Lin G, Fandel TM, Huang YC, Banie L, Breyer BN, Garcia MM, Lin CS, Lue TF. Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo. J Sex Med. 2010 Apr;7(4 Pt 1):1518-28. doi: 10.1111/j.1743-6109.2009.01699.x. Epub 2010 Feb 5. PMID: 20141584; PMCID: PMC3551978.

https://sci-hub.se/https://doi.org/10.1002/9781118543436.ch58

https://www.sciencedirect.com/science/article/pii/S2405844023084347

Punyawudho B, Puttilerpong C, Wirotsaengthong S, Aramwit P. A randomized, double-blind, placebo-controlled crossover study of Cappra® for the treatment of mild or mild to moderate erectile dysfunction in Thai male. Afr J Tradit Complement Altern Med. 2012 Dec 31;10(2):310-5. PMID: 24146455; PMCID: PMC3746578.

Nishimatsu H, Kitamura T, Yamada D, Nomiya A, Niimi A, Suzuki M, Fujimura T, Fukuhara H, Nakagawa T, Enomoto Y, Kume H, Igawa Y, Homma Y. Improvement of symptoms of aging in males by a preparation LEOPIN ROYAL containing aged garlic extract and other five of natural medicines – comparison with traditional herbal medicines (Kampo). Aging Male. 2014 Jun;17(2):112-6. doi: 10.3109/13685538.2013.771328. PMID: 24844765.

Hatzimouratidis K. Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence. Clin Interv Aging. 2006;1(4):403-14. doi: 10.2147/ciia.2006.1.4.403. PMID: 18046917; PMCID: PMC2699643.

Horny Goat Weed

Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol. 1994 Jan;151(1):54-61. doi: 10.1016/s0022-5347(17)34871-1. PMID: 8254833.

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About the Experts

JaXX™

What is Horny Goat Weed (Icariin)?

How Does Viagra Work?

Horny Goat Weed vs. Viagra: What is the Difference?

Is Horny Goat Weed Like Viagra?

Which Is Better for Erectile Dysfunction?

Frequently Asked Questions

Key Takeaways

Jack & Jill Health is not a pharmacy or drug manufacturer.

JackHealth is not a pharmacy
or drug manufacturer.

JackHealth is not a pharmacy
or drug manufacturer.

Horny Goat Weed vs. Viagra: Which is Better for Erectile Dysfunction?

About the Experts

JaXX™

What is Horny Goat Weed (Icariin)?

How Does Viagra Work?

Horny Goat Weed vs. Viagra: What is the Difference?

Is Horny Goat Weed Like Viagra?

Which Is Better for Erectile Dysfunction?

Frequently Asked Questions

Key Takeaways

Jack & Jill Health is not a pharmacy or drug manufacturer.

JackHealth is not a pharmacy or drug manufacturer.

JackHealth is not a pharmacy or drug manufacturer.

Select your store

JackHealth is not a pharmacy
or drug manufacturer.

JackHealth is not a pharmacy
or drug manufacturer.